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Research Article

Spot protein/creatinine ratio as an accurate quantification of proteinuria to  replace the use of the 24 hours urine protein in pre-eclamptic women

Vani Isukapalli1*, Anuradha J2, Padmanvati Thatavarth3 and Swetha4


1-4
Department of OBG, Andhra Medical College, Visakhapatnam, Andhra Pradesh, India

E-mail:
ivani_20@yahoo.com

Abstract
The objective of the study was to know if a spot protein/ creatinine ratio would provide an accurate quantification of proteinuria and whether it can replace the use of the 24 hours urine protein in preeclamptic women. 60 women with preeclampsia were recruited for the study. A stable renal function was ascertained by doing serum creatinine and blood urea nitrogen. The patients were instructed to collect the 24 hours urine starting from the second urine sample in the morning till the first urine sample the next day morning. A single voided urine specimen was obtained thereafter for determination of the protein/ creatinine ratio. The urine protein and creatinine were measured using a standard methods. In the present study it was observed that with proteinuria <300 mg a negative correlation exists between 24 hour urine protein and spot p/c ratio. This observation can be explained by the fact, that, the number of patients in this range of proteinuria was less and also in the exclusion criteria those patients with dipstick <1+ (like traces and negative) is excluded from the study

Keywords: 24 hour urine protein, preeclampsia, spot protein creatinine ratio

Published online 27th April, 2015
2015 Published by
Global Science Publishing Group, USA

Cite this Article as

Vani Isukapalli, Anuradha J, Padmanvati Thatavarth and Swetha. (2015). Spot protein/creatinine ratio as an accurate quantification of proteinuria to  replace the use of the 24 hours urine protein in pre-eclamptic women. The Ame J Sci & Med Res, 1(1):82-91. doi:10.17812/ajsmr2015116
The Ame J Scie & Med Res, Volume 1, Issue 1
DOI: http://dx.doi.org/10.17812/ajsmr2015116
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